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Drama · Comedy · Medical

Best Medicine 2026 (season 2): U.S. release date and where to watch

FOX drama and comedy series, now in its 2nd season.

Airing now FOX Listings updated Listings

Artwork via TVmaze · © its respective owners

Is Best Medicine on tonight?

No new episode tonight. Next up on Best Medicine is episode 8, "Back to the Suture", on Tuesday, November 17, 2026 at 8 p.m. ET / 7 p.m. CT on FOX.

Quick answer · Season 2

Best Medicine season 2 premiered on September 20, 2026 on FOX at 8 p.m. ET / 7 p.m. CT and has 14 episodes.

Episode 8, "Back to the Suture", is on Tuesday, November 17, 2026 at 8 p.m. ET / 7 p.m. CT.

U.S. premiere
September 20, 2026
Where
FOX
Time
8 p.m. ET / 7 p.m. CT
Episodes
14

Watching Best Medicine in Canada?

Where to watch Best Medicine season 2 in the U.S.

Where to watch Best Medicine season 2 in the U.S.
WhereHowWhenNotes
FOX Broadcast (free)Antenna / cable Tuesdays, 8 p.m. ET / 7 p.m. CT [1]

Season 2 episode schedule

Best Medicine season 2 U.S. episode schedule
Ep. Title U.S. date Time Status
1 Be Careful What You Fish For [1] 8 p.m. ET / 7 p.m. CT national slot Listed
2 Breakin' in Is Hard to Do [1] 8 p.m. ET / 7 p.m. CT national slot Listed
3 Crate Expectations [1] 8 p.m. ET / 7 p.m. CT national slot Listed
4 No Place Like Om [1] 8 p.m. ET / 7 p.m. CT national slot Listed
5 Hare Today, Gone Tomorrow [1] 8 p.m. ET / 7 p.m. CT national slot Listed
6 Can't Stop the Healing [1] 8 p.m. ET / 7 p.m. CT national slot Listed
7 Love Is a Battlefield [1] 8 p.m. ET / 7 p.m. CT national slot Listed
8 Back to the Suture [1] 8 p.m. ET / 7 p.m. CT national slot Next
9 The Song Good-Bye [1] 8 p.m. ET / 7 p.m. CT national slot Listed

Dates are U.S. dates. Broadcast times are the network's national slot; your local station may differ.

About Best Medicine

Best Medicine is a drama and comedy series on FOX that first aired in 2026. Season 2 began on Sunday, September 20, 2026, airing Tuesdays 8 p.m. ET/PT (7 p.m. CT).

Season 2: Season 2 of Best Medicine on FOX.

  • Network / service: FOX (first aired January 4, 2026)
  • Official site: fox.com
  • Main cast over the series (TVmaze): Josh Charles (Dr. Martin Best), Abigail Spencer (Louisa Gavin), Josh Segarra (Sheriff Mark Mylow), Annie Potts (Sarah Best), Cree (Elaine Denton)

All seasons

Season 2

Airing now

Season 2 of Best Medicine on FOX.

FOX

Season 1

Streaming

Season 1 aired from 2026-01-04 to 2026-04-07.

FOX

Common questions

When does Best Medicine season 2 come out?

The season premiere is listed for Sunday, September 20, 2026 on FOX. Schedules can change; the table above is updated daily.

What time is Best Medicine on?

FOX lists it Tuesdays at 8 p.m. Eastern and Pacific (7 p.m. Central). Local stations and sports overruns can shift the time.

How many episodes are in season 2?

TVmaze lists 14 episodes for season 2.

Where can I watch Best Medicine?

Best Medicine airs on FOX. Free over the air, or through cable and live-TV streaming services.

When is the next episode of Best Medicine?

Episode 8, "Back to the Suture", of season 2 is on Tuesday, November 17, 2026 (Tuesdays, 8 p.m. ET / 7 p.m. CT).

When was the first episode of Best Medicine season 2?

Season 2 episode 1 premiered on Sunday, September 20, 2026 on FOX.

When does Best Medicine come out in Canada?

In Canada, Best Medicine is on CTV: Tuesdays at 8 p.m. ET, from September 22, 2026, the same night as FOX.

More like Best Medicine

Sources

We check each date against the sources below. If they disagree, we say so rather than picking one.

  1. Best Medicine schedule and episode data
    TVmaze (CC BY-SA) Data Retrieved

Update history

  1. Schedule imported from TVmaze listings.

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